Born in 1980 in Taunton, a son of Glen and Frances (Tighe) Gregory. He has one older brother, Sean. He attended local schools in Taunton, including Joseph H. Martin for both elementary and middle school; and Taunton High School for secondary. He graduated from Merrimack College in North Andover with a bachelor of science in chemistry in 2003, and from Waltham's Brandeis University in 2006 with a master of science in chemistry. He is employed by Vertex Pharmaceuticals, Boston. Married to Nicole (DiVincenzo) Gregory, they are parents of two sons: Cole and Bryce. They are parishioners of St. Joseph Parish, Wakefield. Among other assignments during his deacon formation, he assisted in hospital ministry at Melrose Wakefield, Melrose, and at various liturgical and formation ministries of St. Joseph, Parish.